BDBM50017552 CHEMBL3288309

SMILES [O-][N+](=O)c1ccc2C(Nc3cccc(Br)c3)=NS(=O)(=O)c2c1

InChI Key InChIKey=SHUUNPSCBHSWDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017552   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017552(CHEMBL3288309)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017552(CHEMBL3288309)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed