BDBM50017520 (+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL413105::Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine

SMILES CN(C)C1CCc2ccc3[nH]ccc3c2C1

InChI Key InChIKey=HENBLLXAHPTGHX-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50017520   

TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataIC50: 1.84E+3nMAssay Description:In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataIC50: 82nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataIC50: 1.97E+4nMAssay Description:In vitro binding activity against Dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  24nMAssay Description:Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  66nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in CHO cells (sc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor beta expressed in CHO cells, by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]spiperone from dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50017520((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...)
Affinity DataKi:  383nMAssay Description:In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed