BDBM50017372 4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-benzoic acid methyl ester::CHEMBL17237

SMILES COC(=O)c1ccc(OCCCN2CCC(CC2)C(O)(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=DNJLISQLMWIPEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017372   

TargetHistamine H1 receptor(Guinea pig)
A.H. Robins

Curated by ChEMBL
LigandPNGBDBM50017372(CHEMBL17237 | 4-(3-{4-[Bis-(4-fluoro-phenyl)-hydro...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against Tritiated [3H]- mepyramine binding to Histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed