BDBM50017276 CHEMBL3287679::US10099993, Compound 28

SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccccc2C(O)=O)c(C)c1O

InChI Key InChIKey=SEVOKEKAFIENJT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017276   

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017276(CHEMBL3287679 | US10099993, Compound 28)
Affinity DataEC50:  415nMAssay Description:Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017276(CHEMBL3287679 | US10099993, Compound 28)
Affinity DataEC50:  415nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017276(CHEMBL3287679 | US10099993, Compound 28)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent