BDBM50017236 (4aS,9aR)-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol::4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol::CHEMBL430441

SMILES CC[C@@]12CCN(C)C[C@@H]1Oc1ccc(O)cc21

InChI Key InChIKey=WYHZNSRQYYJYTK-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50017236   

TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholi

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  19nMAssay Description:Binding affinity for mouse opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholi

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  212nMAssay Description:Binding affinity for mouse sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  212nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholi

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi:  1.35E+3nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for mouse opioid receptor kappaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholi

Curated by ChEMBL
LigandPNGBDBM50017236(4aS,9aR-(-)-cis-4a-Ethyl-2-methyl-1,2,3,4,4a,9a-he...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]U69,593 from human recombinant kappa opioid receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed