BDBM50017203 CHEMBL3287379

SMILES c1conc1NC[C@H]2CN(C(=O)O2)c3cc(c(c(c3F)F)N4CCC(=O)C=C4)F

InChI Key InChIKey=SULYVXZZUMRQAX-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017203   

TargetAmine oxidase [flavin-containing] A(Human)
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine as substrate after 30 to 60 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in yeast after 1 hr by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed