BDBM50017072 4-Bromo-N-cyclopropylmethyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL22569

SMILES CN1CCC[C@@]11CCCC[C@@H]1N(CC1CC1)C(=O)c1ccc(Br)cc1

InChI Key InChIKey=CFDWVOCCPAMIBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017072   

TargetMu-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017072(CHEMBL22569 | 4-Bromo-N-cyclopropylmethyl-N-(1-met...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017072(CHEMBL22569 | 4-Bromo-N-cyclopropylmethyl-N-(1-met...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding inhibition against Opioid receptor kappa 1 of guinea pig was determined using [3H]ethylketocyclazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017072(CHEMBL22569 | 4-Bromo-N-cyclopropylmethyl-N-(1-met...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed