BDBM50017043 1-(4-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline::CHEMBL21484

SMILES COc1ccc(cc1)C1NCCc2ccccc12

InChI Key InChIKey=FSFZUYODRIULLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017043   

TargetSigma non-opioid intracellular receptor 1(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017043(CHEMBL21484 | 1-(4-Methoxy-phenyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017043(CHEMBL21484 | 1-(4-Methoxy-phenyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGlucose-induced degradation protein 4 homolog(Human)
Lunenfeld-Tanenbaum Research Institute

Curated by ChEMBL
LigandPNGBDBM50017043(CHEMBL21484 | 1-(4-Methoxy-phenyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed