BDBM50017028 8-(2-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline::CHEMBL442106

SMILES COc1ccccc1-c1cccc2CCNCc12

InChI Key InChIKey=RVFFYFPIZYIKEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017028   

TargetSigma non-opioid intracellular receptor 1(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017028(CHEMBL442106 | 8-(2-Methoxy-phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017028(CHEMBL442106 | 8-(2-Methoxy-phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 900nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50017028(CHEMBL442106 | 8-(2-Methoxy-phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50017028(CHEMBL442106 | 8-(2-Methoxy-phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2018
Entry Details Article
PubMed