BDBM50017002 CHEMBL18559::[4-(7-Chloro-4-hydroxy-3-methyl-5-propyl-benzofuran-2-ylmethyl)-phenoxy]-acetic acid

SMILES CCCc1cc(Cl)c2oc(Cc3ccc(OCC(O)=O)cc3)c(C)c2c1O

InChI Key InChIKey=HTSFWUUXXROXSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017002   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50017002(CHEMBL18559 | [4-(7-Chloro-4-hydroxy-3-methyl-5-pr...)
Affinity DataIC50: 105nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed