BDBM50016995 3-[7-Chloro-4-hydroxy-2-(4-methoxy-benzyl)-3-methyl-benzofuran-5-yl]-propionic acid::CHEMBL274233

SMILES COc1ccc(Cc2oc3c(Cl)cc(CCC(O)=O)c(O)c3c2C)cc1

InChI Key InChIKey=SEFPUCATDWALSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016995   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016995(CHEMBL274233 | 3-[7-Chloro-4-hydroxy-2-(4-methoxy-...)
Affinity DataIC50: 2.13E+3nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed