BDBM50016992 7-Chloro-5-(3-hydroxy-propyl)-2-(4-methoxy-benzyl)-3-methyl-benzofuran-4-ol::CHEMBL18376

SMILES COc1ccc(Cc2oc3c(Cl)cc(CCCO)c(O)c3c2C)cc1

InChI Key InChIKey=SYIHQALWEIPVRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016992   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016992(CHEMBL18376 | 7-Chloro-5-(3-hydroxy-propyl)-2-(4-m...)
Affinity DataIC50: 161nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016992(CHEMBL18376 | 7-Chloro-5-(3-hydroxy-propyl)-2-(4-m...)
Affinity DataIC50: 76nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed