BDBM50016990 2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofuran-4-ol::CHEMBL18394

SMILES CCCc1cc(C)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O

InChI Key InChIKey=QBJUFUHYFMGSJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016990   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(CHEMBL18394 | 2-(4-Methoxy-benzyl)-3,7-dimethyl-5-...)
Affinity DataIC50: 12nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(CHEMBL18394 | 2-(4-Methoxy-benzyl)-3,7-dimethyl-5-...)
Affinity DataIC50: 140nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed