BDBM50016973 3-{4-[4-(2-Bromo-thieno[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL543253

SMILES Brc1cc2c(nccc2s1)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1

InChI Key InChIKey=DRRBJWHZVHKSCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016973   

Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016973(CHEMBL543253 | 3-{4-[4-(2-Bromo-thieno[3,2-c]pyrid...)
Affinity DataIC50: 25nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016973(CHEMBL543253 | 3-{4-[4-(2-Bromo-thieno[3,2-c]pyrid...)
Affinity DataIC50: 116nMAssay Description:Ability to bind at 5-hydroxytryptamine 2 receptor of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016973(CHEMBL543253 | 3-{4-[4-(2-Bromo-thieno[3,2-c]pyrid...)
Affinity DataIC50: 440nMAssay Description:Ability to bind at dopamine receptor D2 of rat corpus striatum by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed