BDBM50016970 4-Piperazin-1-yl-thieno[3,2-c]pyridine; hydrochloride::CHEMBL552833::CHEMBL608135

SMILES C1CN(CCN1)c1nccc2sccc12

InChI Key InChIKey=RVGRTFBJOXMFAX-UHFFFAOYSA-N

Data  1 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016970   

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataIC50: 139nMAssay Description:Ability to bind at alpha-1 adrenergic receptor by displacing [3H]WB-4101More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataIC50: 113nMAssay Description:Ability to bind at alpha-2 adrenergic receptor by displacing [3H]clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataIC50: 71nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataEC50:  187nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataIC50: 141nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to bind at dopamine receptor D2 of rat corpus striatum by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataKi:  14nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed