BDBM50016882 1-Butyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-phenanthren-8-ol::CHEMBL263574

SMILES CCCCN1CCC[C@H]2[C@H]1COc1c(O)cccc21

InChI Key InChIKey=HBUXLNNWKYJTIE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016882   

Target5-hydroxytryptamine receptor 1A(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016882(CHEMBL263574 | 1-Butyl-2,3,4,4a,10,10a-hexahydro-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016882(CHEMBL263574 | 1-Butyl-2,3,4,4a,10,10a-hexahydro-1...)
Affinity DataIC50: 39nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016882(CHEMBL263574 | 1-Butyl-2,3,4,4a,10,10a-hexahydro-1...)
Affinity DataIC50: 260nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]spiperone binding dopamine receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016882(CHEMBL263574 | 1-Butyl-2,3,4,4a,10,10a-hexahydro-1...)
Affinity DataIC50: 8nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed