BDBM50016687 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamide::CHEMBL54453

SMILES CN(O)C(=O)Cc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=MYMPWMRYZURXNI-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016687   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte cyclooxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibitory activity against rat polymorphonuclear leukocyte cyclooxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(CHEMBL54453 | 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-m...)
Affinity DataKi:  1.00E+5nMAssay Description:Activity to bind against [3H]LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed