BDBM50016683 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-hydroxy-N-methyl-acetamide::CHEMBL55620

SMILES CN(O)C(=O)Cc1ccc(OCc2cccc(Cl)c2)cc1

InChI Key InChIKey=JCXGUOPPEAUVFZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016683   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016683(CHEMBL55620 | 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016683(CHEMBL55620 | 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016683(CHEMBL55620 | 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016683(CHEMBL55620 | 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against rat polymorphonuclear leukocyte cyclooxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016683(CHEMBL55620 | 2-[4-(3-Chloro-benzyloxy)-phenyl]-N-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte cyclooxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed