BDBM50016581 (4-Amino-benzenesulfonylamino)-acetic acid::2-(4-aminophenylsulfonamido)acetic acid::CHEMBL285053

SMILES Nc1ccc(cc1)S(=O)(=O)NCC(O)=O

InChI Key InChIKey=BPJUMYMTQYMSFZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016581   

LigandPNGBDBM50016581(CHEMBL285053 | (4-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 1.60E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50016581(CHEMBL285053 | (4-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of aldose reductase in rat lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50016581(CHEMBL285053 | (4-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50016581(CHEMBL285053 | (4-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant Aldose reductase in rat lens using D,L-glyceraldehyde as substrate preincubated for 1 min in presence of NADPH followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed