BDBM50016567 (Toluene-4-sulfonylamino)-acetic acid::CHEMBL287486

SMILES Cc1ccc(cc1)S(=O)(=O)NCC(O)=O

InChI Key InChIKey=VDKFCCZUCXYILI-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016567   

TargetCarbonic anhydrase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of CA-2 (unknown origin) after 15 mins by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataIC50: 8.57E+3nMAssay Description:Inhibition of CA-12 (unknown origin) after 15 mins by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataIC50: 217nMAssay Description:Inhibition of CA-9 (unknown origin) after 15 mins by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CA-1 (unknown origin) after 15 mins by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataKi:  1.44E+5nMAssay Description:Inhibition of cytosolic carbonic anhydrase 2 esterase activity isolated from human erythrocytes using 4-nitrophenylacetate as substrate measured over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50016567(CHEMBL287486 | (Toluene-4-sulfonylamino)-acetic ac...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of cytosolic carbonic anhydrase 1 esterase activity isolated from human erythrocytes using 4-nitrophenylacetate as substrate measured over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed