BDBM50016489 (6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::7,9-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL13866

SMILES C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1

InChI Key InChIKey=VLMZMRDOMOGGFA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50016489   

TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 4.18E+3nMAssay Description:Competition in vitro with the dopamine receptor D2 antagonist [3H]spiperone, for binding sites on calf caudate membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 4.34E+3nMAssay Description:Displacement of [3H]SCH-23390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 1.67E+3nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 2.79E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 440nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from rat frontal cortex homogenates by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50016489((6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-oct...)
Affinity DataIC50: 360nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1 receptor using [3H]5-HT as a radioligand from rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMed