BDBM50015767 CHEMBL269318::Isopropyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl-amine

SMILES CC(C)Nc1nc2ccccc2n2cnnc12

InChI Key InChIKey=XFWPLYABTZBENI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015767   

TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015767(CHEMBL269318 | Isopropyl-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataIC50: 4.10E+3nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015767(CHEMBL269318 | Isopropyl-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataIC50: 1.70E+4nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015767(CHEMBL269318 | Isopropyl-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards adenosine A1 receptor using [3H]N-cyclohexyladenosine in rat whole brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015767(CHEMBL269318 | Isopropyl-[1,2,4]triazolo[4,3-a]qui...)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity against Adenosine-2 receptor with [3H]-NECA in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed