BDBM50015709 5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL27592

SMILES Brc1ccc2[nH]cc(C3=CCNCC3)c2c1

InChI Key InChIKey=FCKKUEPMSPRIAO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015709   

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015709(CHEMBL27592 | 5-Bromo-3-(1,2,3,6-tetrahydro-pyridi...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015709(CHEMBL27592 | 5-Bromo-3-(1,2,3,6-tetrahydro-pyridi...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015709(CHEMBL27592 | 5-Bromo-3-(1,2,3,6-tetrahydro-pyridi...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed