BDBM50015456 CHEMBL3264997

SMILES COc1ccc(Nc2nc(cn3ccnc23)-c2cccc(c2)C(=O)Nc2cccc(c2)C(O)=O)cc1OC

InChI Key InChIKey=XKHQQYBVASUNGW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015456   

TargetTyrosine-protein kinase SYK(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015456(CHEMBL3264997)
Affinity DataEC50:  643nMAssay Description:Inhibition of Syk in antihuman IgM-stimulated human Ramos cells assessed as decrease in BCR-mediated BLNK phosphorylation by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015456(CHEMBL3264997)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed