BDBM50015233 CHEMBL3262727

SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)n1ccc2cccnc12

InChI Key InChIKey=OXPJGPURVBXIAP-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50015233   

TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of HDAC10 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of HDAC9 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed