BDBM50015142 4-Phenylbutyrohydroxamic acid::CHEMBL55895::N-Hydroxy-4-phenyl-butyramide

SMILES c1ccc(cc1)CCCC(=O)NO

InChI Key InChIKey=UPHXPXYRKPCXHK-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50015142   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 2.70E+4nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 2.69E+4nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 4.30E+5nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(CHEMBL55895 | N-Hydroxy-4-phenyl-butyramide | 4-Ph...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed