BDBM50015125 CHEMBL351338::N-Hydroxy-2,N-dimethyl-3-naphthalen-2-yl-acrylamide

SMILES CN(O)C(=O)C(\C)=C\c1ccc2ccccc2c1

InChI Key InChIKey=RFWYMZZGCRBEEN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015125   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015125(CHEMBL351338 | N-Hydroxy-2,N-dimethyl-3-naphthalen...)
Affinity DataIC50: 100nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015125(CHEMBL351338 | N-Hydroxy-2,N-dimethyl-3-naphthalen...)
Affinity DataIC50: 470nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015125(CHEMBL351338 | N-Hydroxy-2,N-dimethyl-3-naphthalen...)
Affinity DataIC50: 470nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed