BDBM50014960 1-Benzyl-1,3-dihydro-imidazole-2-thione::1-Benzyl-1H-imidazole-2-thiol::CHEMBL164791

SMILES S=c1[nH]ccn1Cc1ccccc1

InChI Key InChIKey=AOCFYLGZVCPZML-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50014960   

TargetDopamine beta-hydroxylase(Bovine)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value range from 8.9-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory Concentration against bovine v (DBH); Range is between (20-46).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50014960(CHEMBL164791 | 1-Benzyl-1H-imidazole-2-thiol | 1-B...)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed