BDBM50014913 CHEMBL3262048

SMILES Cc1cc(C)cc(NC2=C(NS(=O)(=O)c3ccccc3)C(=O)c3ccccc3C2=O)c1

InChI Key InChIKey=PUQWEBBQCAJHCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014913   

TargetArylamine N-acetyltransferase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50014913(CHEMBL3262048)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetArylamine N-acetyltransferase 2(Mouse)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50014913(CHEMBL3262048)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged mouse NAT2 expressed in Escherichia coli Rosetta(DE3)pLysS cells assessed as rate of free thiol coen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetArylamine N-acetyltransferase 2(Golden hamster)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50014913(CHEMBL3262048)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of Syrian hamster NAT2 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed