BDBM50014883 CHEMBL3262037

SMILES CC(C)Cn1cc(cn1)-c1c(C)nc2c(nccn12)N1CCOCC1

InChI Key InChIKey=SHZBBHMGMXJFNW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014883   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50014883(CHEMBL3262037)Copy SMILESCopy InChI

Affinity DataIC50: 145nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2015
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50014883(CHEMBL3262037)Copy SMILESCopy InChI

Affinity DataIC50: 145nMAssay Description:Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/3/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL