BDBM50014757 (4-Chloro-phenyl)-(2-chloro-phenyl)-pyridin-3-yl-methanol : (Hydrochloride)::CHEMBL137192

SMILES OC(c1ccc(Cl)cc1)(c1cccnc1)c1ccccc1Cl

InChI Key InChIKey=AKDCDVNDPAZRSM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014757   

TargetAromatase(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014757(CHEMBL137192 | (4-Chloro-phenyl)-(2-chloro-phenyl)...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50014757(CHEMBL137192 | (4-Chloro-phenyl)-(2-chloro-phenyl)...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed