BDBM50014725 6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL127924

SMILES CC(C)c1nn(c(c1CC[C@@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccccc1

InChI Key InChIKey=GTJZNUCKMJCREJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014725   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50014725(CHEMBL127924 | 6-{2-[5-(4-Fluoro-phenyl)-3-isoprop...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibitory activity against HMG-CoA reductase by employing a crude liver homogenate derived from rats fed a chow diet containing 5% cholesty...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed