BDBM50014669 6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL440891

SMILES Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1

InChI Key InChIKey=BNIBDNOALUGLCI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014669   

LigandPNGBDBM50014669(CHEMBL440891 | 6-[2-(4'-Fluoro-3,5,3'-trimethyl-bi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50014669(CHEMBL440891 | 6-[2-(4'-Fluoro-3,5,3'-trimethyl-bi...)
Affinity DataIC50: 10nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50014669(CHEMBL440891 | 6-[2-(4'-Fluoro-3,5,3'-trimethyl-bi...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50014669(CHEMBL440891 | 6-[2-(4'-Fluoro-3,5,3'-trimethyl-bi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed