BDBM50014469 (S)-2-(4-((3-hydroxypropyl)((2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)amino)benzamido)pentanedioic acid::2-{4-[(3-Hydroxy-propyl)-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL104748

SMILES Cc1nc2ccc(CN(CCCO)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=KMIALRSTGSQGJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014469   

TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014469(CHEMBL104748 | 2-{4-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 540nMAssay Description:Binding affinity against Thymidylate synthase was measured in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014469(CHEMBL104748 | 2-{4-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 540nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Meerut Institute of Engineering and Technology

Curated by ChEMBL
LigandPNGBDBM50014469(CHEMBL104748 | 2-{4-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 537nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed