BDBM50014439 CHEMBL3261420

SMILES C[C@@H](CCc1cccc2n(ncc12)-c1ccc(F)cc1)NS(=O)(=O)c1c(C)cc(C)cc1C

InChI Key InChIKey=GAWBCIJNUIGZPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014439   

TargetGlucocorticoid receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50014439(CHEMBL3261420)
Affinity DataIC50: 23nMAssay Description:Agonist activity at glucocorticoid receptor in human Chago K1 cells assessed as gene transrepression by Lac-Z reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50014439(CHEMBL3261420)
Affinity DataIC50: 4.60nMAssay Description:Binding affinity to human glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50014439(CHEMBL3261420)
Affinity DataIC50: 12nMAssay Description:Agonist activity at glucocorticoid receptor in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed