BDBM50014229 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline-10-carbonitrile; hydrochloride::CHEMBL545724

SMILES CSc1ccc(cc1)C1CN2CCCC2c2c(cccc12)C#N

InChI Key InChIKey=AMUJCSFRPIATDU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014229   

TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014229(CHEMBL545724 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5...)
Affinity DataKi:  15nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014229(CHEMBL545724 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5...)
Affinity DataKi:  390nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014229(CHEMBL545724 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5...)
Affinity DataKi:  2.80E+3nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed