BDBM50014226 10-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrochloride::CHEMBL554191

SMILES CSc1ccc(cc1)C1CN2CCC[C@@H]2c2c(Cl)cccc12

InChI Key InChIKey=TXNKGWKKEXRIAI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014226   

TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014226(CHEMBL554191 | 10-Chloro-6-(4-methylsulfanyl-pheny...)
Affinity DataKi:  3nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014226(CHEMBL554191 | 10-Chloro-6-(4-methylsulfanyl-pheny...)
Affinity DataKi:  23nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014226(CHEMBL554191 | 10-Chloro-6-(4-methylsulfanyl-pheny...)
Affinity DataKi:  290nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed