BDBM50014224 8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrochloride::CHEMBL555655

SMILES CSc1ccc(cc1)C1CN2CCCC2c2ccc(Cl)cc12

InChI Key InChIKey=JSGXTZMCQYACBY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014224   

TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014224(CHEMBL555655 | 8-Chloro-6-(4-methylsulfanyl-phenyl...)
Affinity DataKi:  8.60nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014224(CHEMBL555655 | 8-Chloro-6-(4-methylsulfanyl-phenyl...)
Affinity DataKi:  16nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014224(CHEMBL555655 | 8-Chloro-6-(4-methylsulfanyl-phenyl...)
Affinity DataKi:  103nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed