BDBM50014113 3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alpha-hexahydropyrrolo[2,3-b]indol-5-ylmethylcarbamate::CHEMBL75729::Methyl-carbamic acid 3a,8-dimethyl-1-phenethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester

SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(CCc4ccccc4)CC[C@@]3(C)c2c1

InChI Key InChIKey=SUYCPJVAABOKNP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50014113   

TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Butyrylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against Acetylcholinesterase in erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against Acetylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014113(CHEMBL75729 | Methyl-carbamic acid 3a,8-dimethyl-1...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed