BDBM50014112 CHEMBL74257::Methyl-carbamic acid 1-benzyl-3a,8-dimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester

SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(Cc4ccccc4)CC[C@@]3(C)c2c1

InChI Key InChIKey=GVJXSDRIRBRKBI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50014112   

TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Acetylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against Butyrylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against Acetylcholinesterase in erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed