BDBM50014095 CHEMBL3260850

SMILES Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2cccc(Cl)c2)on1

InChI Key InChIKey=LITPAOYSUGZCNV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014095   

TargetElongin-B/Elongin-C/von Hippel-Lindau disease tumor suppressor(Human)
University of Utah

Curated by ChEMBL

LigandBDBM50014095(CHEMBL3260850)Copy SMILESCopy InChI

Affinity DataIC50: 1.17E+5nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
2/9/2015
Entry Details Article
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Targetvon Hippel-Lindau disease tumor suppressor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50014095(CHEMBL3260850)Copy SMILESCopy InChI

Affinity DataIC50: 1.17E+5nMAssay Description:Binding affinity to VHL E3 ligase (unknown origin) by fluorescence polarization (FP) assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL