BDBM50014083 (R)-2-Benzyl-4-((3R,4S)-3,4-bis-methoxymethoxy-pyrrolidin-1-yl)-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-2-((S)-3-ethyl-2-oxo-oxazolidin-5-yl)-2-hydroxy-ethylcarbamoyl]-2-(3H-imidazol-4-yl)-ethyl]-4-oxo-butyramide::CHEMBL59887

SMILES CCN1C[C@H](OC1=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](CC(=O)N1C[C@@H](OCOC)[C@H](C1)OCOC)Cc1ccccc1

InChI Key InChIKey=XDZOMKZUBUHOHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014083   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014083((R)-2-Benzyl-4-((3R,4S)-3,4-bis-methoxymethoxy-pyr...)
Affinity DataIC50: 11nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014083((R)-2-Benzyl-4-((3R,4S)-3,4-bis-methoxymethoxy-pyr...)
Affinity DataIC50: 2.70nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed