BDBM50013061 (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL106622

SMILES CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key InChIKey=TVIUJNLDORXPPC-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50013061   

TargetD(1A) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity against Dopamine receptor D1 from rat brain corpus striatum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataIC50: 0.0710nMAssay Description:Binding affinity against Dopamine receptor D2 from rat brain corpus striatum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]SCH-23390 from rat dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataIC50: 0.0710nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]domperidone from human cloned dopamine D3 receptor high binding site expressed in mouse CCL1-3 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50013061((R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-diben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed