BDBM50012951 4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4-yl-2-naphthalen-1-ylmethyl-4-oxo-butyrylamino)-propionylamino]-butyric acid isopropyl ester::CHEMBL3350322

SMILES CC(C)OC(=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](CC(=O)N1CCOCC1)Cc1cccc2ccccc12

InChI Key InChIKey=NQXSBCTYTMQGGJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012951   

TargetRenin(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 2.40nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition of Chymotrypsinogen from bovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetPepsin A(Pig)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition of pepsin from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetRenin(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 4.70nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 8.00E+4nMAssay Description:Tested for inhibition of Cathepsin D from bovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition of Angiotensin I converting enzyme from rabbit.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed