BDBM50012950 2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4-yl-2-naphthalen-1-ylmethyl-4-oxo-butyrylamino)-propionylamino]-5-methyl-hexanoic acid isopropyl ester::CHEMBL330074

SMILES CC(C)C[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](CC(=O)N1CCOCC1)Cc1cccc2ccccc12)C(O)C(=O)OC(C)C

InChI Key InChIKey=LAQXJGUAIIHFMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012950   

TargetRenin(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012950(CHEMBL330074 | 2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2...)
Affinity DataIC50: 6.70nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetRenin(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012950(CHEMBL330074 | 2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2...)
Affinity DataIC50: 6.20nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed