BDBM50012934 CHEMBL307388::N-(2-Cyclohexyl-1-cyclohexylmethyl-2-hydroxy-ethyl)-3-(1H-imidazol-4-yl)-2-(8-isobutyl-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-propionamide. H2O

SMILES CC(C)Cc1nc(cn2c(nnc12)C(Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)C(O)C1CCCCC1)-c1ccccc1

InChI Key InChIKey=NNBHDRJEVSYTPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012934   

TargetRenin(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012934(CHEMBL307388 | N-(2-Cyclohexyl-1-cyclohexylmethyl-...)
Affinity DataIC50: 330nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed