BDBM50012892 2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxy-N-isopropyl-acetamide(Indomethacin series)::CHEMBL303199

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N(O)C(C)C)c2c1

InChI Key InChIKey=XGXXAGGMMNRRPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012892   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012892(CHEMBL303199 | 2-[1-(4-Chloro-benzoyl)-5-methoxy-2...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012892(CHEMBL303199 | 2-[1-(4-Chloro-benzoyl)-5-methoxy-2...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed