BDBM50012877 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-carboxylic acid (5-methyl-thiazol-2-yl)-amide::CHEMBL63546

SMILES Cc1cnc(NC(=O)C2C(=O)N3c4c2cccc4Cc2cc(F)ccc32)s1

InChI Key InChIKey=KAKKGJNQTKAXMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012877   

LigandPNGBDBM50012877(CHEMBL63546 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012877(CHEMBL63546 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed