BDBM50012863 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-carboxylic acid (2,5-difluoro-phenyl)-amide::CHEMBL64396

SMILES Fc1ccc2N3C(=O)C(C(=O)Nc4cc(F)ccc4F)c4cccc(Cc2c1)c34

InChI Key InChIKey=UYDYGHBMEHKGCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012863   

LigandPNGBDBM50012863(CHEMBL64396 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012863(CHEMBL64396 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed