BDBM50012841 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]azepino[3,2,1-hi]indole-2-carboxylic acid (2,4-difluoro-phenyl)-amide::CHEMBL64337

SMILES Fc1ccc(NC(=O)C2C(=O)N3c4c2cccc4CCc2ccccc32)c(F)c1

InChI Key InChIKey=GVIHCQGAPIJNIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012841   

LigandPNGBDBM50012841(CHEMBL64337 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012841(CHEMBL64337 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed